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St. John’s vs Duke Prediction, Picks & Odds for Today's March Madness Game

St. John’s is in for a tough night offensively in our St. John’s vs. Duke predictions, odds and March Madness picks for the Sweet 16 matchup on Friday, March 27, 2026.

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St. John’s vs Duke Prediction, Picks & Odds for Today's March Madness Game

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